Bacillus Vallismortis, a Gram-positive bacterium, was isolated from soil. This strain possesses a number of genes encoding virulence factors of pathogens. Bacillus vallismortis is a bacterial species in the genus Bacillus with a high affinity for B. subtilis. In its growth process, Bacillus vallismortis can produce numerous antimicrobial bioactive metabolites, such as thermostable alkalophilic cellulase and bafilomycin. These antibiotic compounds may provide alternative resources for the biocontrol of plant diseases. Strain belongs to the species Bacillus vallismortis. The type strain of the species produces many bioactive metabolites showing specific activity against Fusarium oxysporum f. sp. niveum, which causes watermelon wilt disease, the most destructive disease to melon crops worldwide.